Prophylactic methylprednisolone for cardiac surgery in infants does not improve postoperative outcomes | Medicine in 2 Minutes
1. In infants undergoing cardiopulmonary bypass surgery, prophylactic use of methylprednisolone did not significantly reduce composite mortality, heart transplantation, complications, and prolonged hospital stay. 2. Prophylactic use of methylprednisolone was associated with an increased risk of postoperative hyperglycemia. Level of evidence assessment: 1 (Excellent) Summary of the study: Perioperative glucocorticoids have been used for decades …