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Metformin monotherapy not always the best start in type 2 diabetes

Metformin monotherapy not always the best start in type 2 diabetes

Metformin failure in people with type 2 diabetes is very common, especially in those with elevated A1c levels at diagnosis, new findings suggest. An analysis of electronic health record data from more than 22,000 patients starting metformin at three US clinical sites found that more than 40% experienced metformin failure. This was defined as the …

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New AHA Statement on Complementary Medicine in Heart Failure

New AHA Statement on Complementary Medicine in Heart Failure

There are some potentially serious benefits and risks associated with complementary and alternative medicine (CAM) that patients with heart failure (HF) can use to manage symptoms, the American Heart Association (AHA) says in a new scientific statement on the subject. For example, yoga and tai chi may be helpful for people with heart failure, and …

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Perceived discrimination linked to worse recovery after MI in young people

Perceived discrimination linked to worse recovery after MI in young people

Perceived discrimination — unfair treatment because of their race, gender, ethnicity, socioeconomic status, or other factors — in daily life was common among young survivors of myocardial infarction (MI) and was associated with poorer recovery, new research shows. In this study, patients completed three questionnaires assessing perceived discrimination, general mental and physical health, physical health, …

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Deaths from heart disease have increased during COVID after 10 years of decline

Deaths from heart disease have increased during COVID after 10 years of decline

Editor’s Note: Find the latest COVID-19 news and advice in Medscape’s Coronavirus Resource Center. Annual deaths from heart disease in the United States increased in 2020 during the COVID pandemic, after a steady decline over the previous decade, a new study has found. The heart disease death rate in the general population rebounded in 2020 …

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Breaking Down Silos: How One Physician Is Reshaping Medicine |  BioSpace

Breaking Down Silos: How One Physician Is Reshaping Medicine | BioSpace

Dr. Kiana Aran, courtesy of Keck Graduate Institute (KGI) As a young woman in Iran, Dr. Kiana Aran made the choice to study electrical engineering. She didn’t know it at the time, but it would lead her to her true passion: biology. It was also the decision that ultimately led her to achieve significant breakthroughs …

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Breaking Down Silos: How One Physician Is Reshaping Medicine |  BioSpace

Breaking Down Silos: How One Physician Is Reshaping Medicine | BioSpace

Dr. Kiana Aran, courtesy of Keck Graduate Institute (KGI) As a young woman in Iran, Dr. Kiana Aran made the choice to study electrical engineering. She didn’t know it at the time, but it would lead her to her true passion: biology. It was also the decision that ultimately led her to achieve significant breakthroughs …

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(PRNewsfoto/Ionis Pharmaceuticals, Inc.)

Ionis Presents Positive Phase 2 Data from Donidalorsen Open-Label Extension Study at the 2022 ACAAI Annual Meeting | BioSpace

Interim Results Show Sustained Reduction in Hereditary Angioedema Attacks and No New Safety Signals in Patients Treated for One Year CARLSBAD, Calif., Nov. 13, 2022 /PRNewswire/ — Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) today reported positive results from a Phase 2 open-label extension (OLE) study evaluating the safety and efficacy of its investigational antisense drug, donidalorsen, …

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New Trial Suggests CV Benefit With EPA: RESPECT-EPA

New Trial Suggests CV Benefit With EPA: RESPECT-EPA

A new Japanese study of highly purified eicosapentaenoic acid (EPA; icosapent ethyl) has suggested a possible benefit in reducing adverse cardiovascular events in patients with chronic coronary heart disease taking statins. The randomized, open-label RESPECT-EPA study showed reduction in borderline statistical significance in its primary endpoint of a composite of cardiovascular death, nonfatal myocardial infarction …

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Lutris Logo (PRNewsfoto/Lutris Pharma)

Lutris Pharma Founder and Chairman Receives $5.0 Million Grant from California Institute of Regenerative Medicine (CIRM) to Develop LUT017 for Wound Healing | BioSpace

TEL AVIV, Israel, October 24, 2022 /PRNewswire/ — Lutris Pharma, a clinical-stage biopharmaceutical company focused on improving cancer therapies by reducing dose-limiting side effects, today announced that the California Institute of Regenerative Medicine (CIRM) has awarded the founder and chairman of the company’s board of directors, Antoine RibasMD, Ph.D., Professor of Medicine, Professor of Surgery, …

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